Entwicklung und Kultivierung von Geweben

• Explain and apply fundamental scientific principles as well as advanced, specialized knowledge in tissue engineering and regenerative medicine. • Describe the basic structure of tissues and analyze interactions between cells and the extracellular matrix. • Explain key developmental processes in mammals and relate them to tissue engineering strategies. • Identify and explain the core components of tissue engineering, including cells, signaling molecules, biomaterials, bioreactors, and three-dimensional (3D) cell culture systems. • Distinguish between different cell-based therapies and evaluate their roles as therapeutic concepts in regenerative medicine. • Analyze and discuss 3D cell culture approaches and evaluate their relevance for tissue engineering, disease modeling, toxicology and pharmacology and translational research. • Develop independent ideas and concepts for solving scientific problems related to tissue engineering.

Written Examination (120 min)

Die einzigen Termine im WiSe 26/27 sind Prüfungstermine – gelehrt wird das Modul in diesem Semester nicht.

• Molecular Biology of The Cell, Alberts et al., 5th/6th edition, Garland Sciences, 2008/2015
• Cell and Molecular Biology. Concepts and experiments. Karp G., John Wiley & Sons, 2008
• Principles of Tissue Engineering, Lanza R. P. et al., Academic Press, 2nd edition 2000
• Methods of Tissue Engineering, Anthony Atala, Robert P. Lanza (eds.), Academic Press, New York, 2002
• Tissue Engineering, Clemens van Blitterswijk (senior editor), Elsevier, Amsterdan,Boston, Heidelberg, … (2008)
• Functional Tissue Engineering, Farshid Guilak, David L. Butler, Steven A. Goldstein, David Mooney, C. MacLachlan, Springer, New York, Berlin, 2003
• Specific original scientific publications

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